BDBM278874 2-{[(1R,2S)-2-amino- cyclohexyl]amino}- N-(4-bromothiophen- 3-yl)thieno[2,3-b] pyrazine-7- carboxamide trifluoroacetate::US10040802, Example 53
SMILES OC(=O)C(F)(F)F.N[C@H]1CCCC[C@H]1Nc1cnc2scc(C(=O)Nc3cscc3Br)c2n1
InChI Key InChIKey=GVCILKLDPWJHIT-ZVWHLABXSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278874
Affinity DataIC50: 0.600nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair