BDBM278885 N-(2-bromothiophen-3- yl)-2-[(1S,4S)- or (1R,4R)-2,5- diazabicylo[2.2.2]oct- 2-yl]thieno[2,3-b] pyrazine-7- carboxamide trifluoroacetate::US10040802, Example 64
SMILES OC(=O)C(F)(F)F.Brc1sccc1NC(=O)c1csc2ncc(nc12)N1C[C@H]2CC[C@@H]1CN2
InChI Key InChIKey=UERMRPORBBEXHH-DHTOPLTISA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278885
Affinity DataIC50: 767nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair