BDBM278892 2-{[(1R,2R)-2-amino- 3,3-difluorocyclohexyl] amino}-N-(2- bromothiophen-3-yl) thieno[2,3-b] pyrazine-7- carboxamide trifluoroacetate::US10040802, Example 71
SMILES OC(=O)C(F)(F)F.N[C@@H]1[C@@H](CCCC1(F)F)Nc1cnc2scc(C(=O)Nc3ccsc3Br)c2n1
InChI Key InChIKey=FJMICBZNCMNOLR-BDROLASLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278892
Affinity DataIC50: 2.07E+3nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair