BDBM278896 2-[(1S,4S)- or (1R,4R)- 2,5-diazabicyclo [2.2.2]oct-2-yl]-N- [2-(trifluoromethyl) thiophen-3-yl] thieno[2,3-b] pyrazine-7- carboxamide trifluoroacetate::US10040802, Example 75
SMILES OC(=O)C(F)(F)F.FC(F)(F)c1sccc1NC(=O)c1csc2ncc(nc12)N1C[C@H]2CC[C@@H]1CN2
InChI Key InChIKey=VWCRPAJRBGVRHT-DHTOPLTISA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278896
Affinity DataIC50: 1.23E+3nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair