BDBM278929 N-(4- chlorothiophen- 3-yl)-2-[(1S,4S)- or (1R,4R)-2,5- diazabicyclo- [2.2.2]oct-2-yl]- thieno[2,3-b]- pyrazine-7- carboxamide trifluoroacetate::US10040802, Example 109
SMILES OC(=O)C(F)(F)F.Clc1cscc1NC(=O)c1csc2ncc(nc12)N1C[C@H]2CC[C@@H]1CN2
InChI Key InChIKey=HRNVPXJXLLHGQV-DHTOPLTISA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 278929
Affinity DataIC50: 104nMpH: 7.2Assay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair