BDBM27941 N-{[(2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylamino)propanamido]butanoyl]pyrrolidin-2-yl]methyl}naphthalene-1-carboxamide::butoxycarbonylpyrrolidine derivative, 15b

SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N1CCC[C@H]1CNC(=O)c1cccc2ccccc12)C(C)(C)C

InChI Key InChIKey=FPXSXLPIQWNRHT-LQBOVUBWSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27941   

LigandPNGBDBM27941(N-{[(2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylami...)
Affinity DataKi:  780nM ΔG°:  -8.24kcal/molepH: 7.2 T: 2°CAssay Description:Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase XIAP [241-356](Homo sapiens (Human))
Genentech

LigandPNGBDBM27941(N-{[(2S)-1-[(2S)-3,3-dimethyl-2-[(2S)-2-(methylami...)
Affinity DataKi:  1.60E+3nMAssay Description:Samples for fluorescence polarization affinity measurements were prepared by addition of serial dilutions of target protein to each well containing a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed