BDBM279483 (R)-1-(1-ethyl-6-(pyridin-4-yl)-1H-benzo[d]imidazol-2-yl)-3-methylbutan-1-amine::US10035777, Example 33

SMILES CCn1c(nc2ccc(cc12)-c1ccncc1)[C@@H](CC(C)C)NC(=O)OCc1ccccc1

InChI Key InChIKey=NHBDOJLFEKYLSW-XMMPIXPASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 279483   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM279483((R)-1-(1-ethyl-6-(pyridin-4-yl)-1H-benzo[d]imidazo...)
Affinity DataIC50:  108nMpH: 7.4 T: 2°CAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent