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BDBM279497 (R)-1-(5-methoxy-6-(pyridin-4-yl)-1H-benzo[d]imidazol-2-yl)-3-methylbutan-1-amine::US10035777, Example 47

SMILES: COc1cc(N)c(NC(=O)[C@@H](CC(C)C)NC(=O)OCc2ccccc2)cc1Br

InChI Key: InChIKey=ZUILMRQNLTWOOZ-GOSISDBHSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 279497   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AP2-associated protein kinase 1


(Homo sapiens)
BDBM279497
PNG
((R)-1-(5-methoxy-6-(pyridin-4-yl)-1H-benzo[d]imida...)
Show SMILES COc1cc(N)c(NC(=O)[C@@H](CC(C)C)NC(=O)OCc2ccccc2)cc1Br
Show InChI InChI=1S/C21H26BrN3O4/c1-13(2)9-18(25-21(27)29-12-14-7-5-4-6-8-14)20(26)24-17-10-15(22)19(28-3)11-16(17)23/h4-8,10-11,13,18H,9,12,23H2,1-3H3,(H,24,26)(H,25,27)/t18-/m1/s1
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
UniChem
n/an/a 487n/an/an/an/an/an/a



Bristol-Myers Squibb Company

US Patent


Assay Description
The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...


US Patent US10035777 (2018)

More data for this
Ligand-Target Pair