BDBM28013 N-(2H-1,3-benzodioxol-5-ylmethyl)-4-(2,6-dimethoxypyridin-3-yl)-5-(1,2,3,4-tetrahydroisoquinolin-2-ylcarbonyl)pyrimidin-2-amine::trisubstituted pyrimidine analogue, 11n

SMILES COc1ccc(c(OC)n1)-c1nc(NCc2ccc3OCOc3c2)ncc1C(=O)N1CCc2ccccc2C1

InChI Key InChIKey=OZXGGGXGTIWICH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28013   

TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Bristol-Myers Squibb

LigandPNGBDBM28013(N-(2H-1,3-benzodioxol-5-ylmethyl)-4-(2,6-dimethoxy...)
Affinity DataIC50:  360nMAssay Description:Antagonist activity of test compounds was measured in HEK293 cells stably expressing the human recombinant CaR (HEK-CaR) by determining the ability o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed