BDBM280422 US10030012, Example 52::ethyl 4-{4-[2- (difluoro- methoxy) pyridin-3- yl]piperidin-1- yl}azepane-1- carboxylate

SMILES CCOC(=O)N1CCCC(CC1)N1CCC(CC1)c1cccnc1OC(F)F

InChI Key InChIKey=MIWAPVKACXIBKZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 280422   

TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM280422(US10030012, Example 52 | ethyl 4-{4-[2- (difluoro-...)
Affinity DataEC50: >1.00E+7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M4(Homo sapiens (Human))
Heptares Therapeutics

US Patent
LigandPNGBDBM280422(US10030012, Example 52 | ethyl 4-{4-[2- (difluoro-...)
Affinity DataEC50:  10nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent