BDBM281117 US10022354, Example 57

SMILES CC(C)c1cc([nH]n1)C(=O)N1CCC(C1)c1cc(NS(=O)(=O)c2ccccc2)cc(C)n1

InChI Key InChIKey=PJUURNQOAWVMOA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 281117   

TargetLysine-specific demethylase 5A(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM281117(US10022354, Example 57)
Affinity DataIC50:  17nMpH: 7.0 T: 2°CAssay Description:Full length KDM5A enzyme was expressed and purified inhouse. Biotin-H3K4me3 peptide was purchased from New England Biolabs. HTRF reagents (containing...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent