BDBM28135 methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H-carbazol-2-yl]-2-[(2-chlorobenzene)sulfonyl]propanoate::tetrahydro-carbazole, (+/-)15

SMILES [H][C@]1(CCc2c(C1)[nH]c1ccc(Cl)cc21)[C@@](C)(C(=O)OC)S(=O)(=O)c1ccccc1Cl

InChI Key InChIKey=GVGFPQNEINNGIL-DMZKTXOQSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28135   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28135(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  800nM EC50:  1.53E+3nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28135(methyl (2S)-2-[(2R)-6-chloro-2,3,4,9-tetrahydro-1H...)
Affinity DataIC50:  540nM EC50:  2.08E+3nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed