BDBM28154 5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl]fluoromethyl]-N,N-dimethyl-1,2,4-oxadiazol-3-amine::tetrahydro-cyclopenta[b]indole, (+/-)28c

SMILES [H][C@@]1(Cc2[nH]c3ccc(Cl)cc3c2C1)[C@@](F)(c1nc(no1)N(C)C)S(=O)(=O)c1ccccc1

InChI Key InChIKey=LIBSEWDVSYHTJA-DMZKTXOQSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28154   

TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28154(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  13nM EC50:  120nMAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-alpha(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM28154(5-[(S)-(benzenesulfonyl)[(2R)-7-chloro-1H,2H,3H,4H...)
Affinity DataIC50:  29nM EC50:  370nMpH: 7.4 T: 2°CAssay Description:LXR receptor binding assays were performed in 96-well plates. For each well reaction, GST-LXR-LBD fusion proteins were bound to SPA beads, and radiol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed