BDBM281769 2-(3 -(1H-py rrolo[2,3-b]pyridin- 3-yl)benzylamino)-N- (cyclopentylmethyl)nicotinamide::US10030016, Example 1.8

SMILES O=C(NCC1CCCC1)c1cccnc1NCc1cccc(c1)-c1c[nH]c2ncccc12

InChI Key InChIKey=XKNAYULLVUTQST-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 281769   

Target3-phosphoinositide-dependent protein kinase 1 [51-359](Homo sapiens (Human))
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM281769(2-(3 -(1H-py rrolo[2,3-b]pyridin- 3-yl)benzylamino...)
Affinity DataIC50:  550nMAssay Description:PDK1 (amino acids 51-359) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) were expressed as N-terminally tagged GST fusi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent