BDBM28178 3-[(2-chlorophenyl)methoxy]-5-(5,6-dimethoxy-1H-1,3-benzodiazol-1-yl)thiophene-2-carboxamide::BMCL191694 Compound 2::benzimidazole thiophene analogue, 29

SMILES COc1cc2ncn(-c3cc(OCc4ccccc4Cl)c(s3)C(N)=O)c2cc1OC

InChI Key InChIKey=WRWFZZDBIJLBIJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 28178   

TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Gsk

LigandPNGBDBM28178(3-[(2-chlorophenyl)methoxy]-5-(5,6-dimethoxy-1H-1,...)
Affinity DataIC50:  2nMpH: 7.2 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified PLK enzyme and biotinylated peptide substrate in the presence ATP/[gamma-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Gsk

LigandPNGBDBM28178(3-[(2-chlorophenyl)methoxy]-5-(5,6-dimethoxy-1H-1,...)
Affinity DataIC50:  2nMpH: 7.2 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified PLK enzyme and biotinylated peptide substrate in the presence ATP/[gamma-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Gsk

LigandPNGBDBM28178(3-[(2-chlorophenyl)methoxy]-5-(5,6-dimethoxy-1H-1,...)
Affinity DataIC50:  9nMpH: 7.2 T: 2°CAssay Description:The compound inhibitory activity was determined by incubation with purified PLK enzyme and biotinylated peptide substrate in the presence ATP/[gamma-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed