BDBM282756 5-(3,5-Difluorophenoxy)-2,2-difluoro-3- hydroxy-3-methyl-2,3- dihydrobenzo[b]thiophene-4-carbonitrile 1,1- dioxide::US9884843, Compound 100

SMILES CC1(O)c2c(ccc(Oc3cc(F)cc(F)c3)c2C#N)S(=O)(=O)C1(F)F

InChI Key InChIKey=DUSPIEVHQZJGAO-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 282756   

TargetVascular endothelial growth factor A(Homo sapiens (Human))
Peloton Therapeutics

US Patent
LigandPNGBDBM282756(5-(3,5-Difluorophenoxy)-2,2-difluoro-3- hydroxy-3-...)
Affinity DataEC50:  18nMAssay Description:About 7500 of 786-O cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
Peloton Therapeutics

US Patent
LigandPNGBDBM282756(5-(3,5-Difluorophenoxy)-2,2-difluoro-3- hydroxy-3-...)
Affinity DataIC50:  41nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent