BDBM283362 N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((6-(methylsulfonyl)quinolin-3- yl)methyl)isonicotinamide::US10023557, Example 14::US10266515, Example 14::US10308637, Example 14::US11021463, Example 14::US9611252, Example 14
SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccnc(Cc2cnc3ccc(cc3c2)S(C)(=O)=O)c1
InChI Key InChIKey=IISORMHFXQMHMH-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 283362
Affinity DataIC50: 550nMpH: 7.5Assay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:The ability of the compounds disclosed herein to inhibit human plasma kallikrein activity was quantified according to the procedures below.A 10 mM so...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Lifesci Pharmaceuticals
US Patent
Lifesci Pharmaceuticals
US Patent
Affinity DataIC50: 550nMAssay Description:A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...More data for this Ligand-Target Pair