BDBM283712 4-(azetidin-3-yloxy)-N-(4-chloro-3-(trifluoromethyl)phenyl)benzamide::US10023559, Example 37

SMILES FC(F)(F)c1cc(NC(=O)c2ccc(OC3CNC3)cc2)ccc1Cl

InChI Key InChIKey=IXKXGTJHXAUXHK-UHFFFAOYSA-N

Data  1 KI  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 283712   

TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM283712(4-(azetidin-3-yloxy)-N-(4-chloro-3-(trifluoromethy...)
Affinity DataKi:  2.60nMpH: 7.4Assay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM283712(4-(azetidin-3-yloxy)-N-(4-chloro-3-(trifluoromethy...)
Affinity DatapH: 7.4Assay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent