BDBM28376 N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-yl}-N-cyclopropyl-4-[(2S)-1,1,1-trifluoro-2-hydroxypropan-2-yl]benzamide::piperidyl benzamide derivative, 15

SMILES C[C@](O)(c1ccc(cc1)C(=O)N(C1CC1)C1CCN(CC2(CC2)C(N)=O)CC1)C(F)(F)F

InChI Key InChIKey=FAVXIEFZKPJZRT-NRFANRHFSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28376   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

LigandPNGBDBM28376(N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-y...)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair