BDBM28458 (2R)-3-methyl-2-{[11-(propane-2-sulfonamido)-8-oxatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6,10,12-hexaene-4-]sulfonamido}butanoic acid::dibenzofuran (DBF) scaffold, (R)-4

SMILES CC(C)[C@@H](NS(=O)(=O)c1ccc2oc3cc(NS(=O)(=O)C(C)C)ccc3c2c1)C(O)=O

InChI Key InChIKey=SMWVRODLVRVTBW-LJQANCHMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28458   

TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28458((2R)-3-methyl-2-{[11-(propane-2-sulfonamido)-8-oxa...)
Affinity DataIC50:  120nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28458((2R)-3-methyl-2-{[11-(propane-2-sulfonamido)-8-oxa...)
Affinity DataIC50:  50nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed