BDBM28462 (2S)-3-methyl-2-{[12-(2,2,2-trifluoroethane-1-sulfonamido)-8-oxatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-5-]sulfonamido}butanoic acid::dibenzofuran (DBF) scaffold, (S)-8

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)oc1ccc(NS(=O)(=O)CC(F)(F)F)cc21)C(O)=O

InChI Key InChIKey=RBTRVKIWYJFOJW-KRWDZBQOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28462   

TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28462((2S)-3-methyl-2-{[12-(2,2,2-trifluoroethane-1-sulf...)
Affinity DataIC50:  670nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28462((2S)-3-methyl-2-{[12-(2,2,2-trifluoroethane-1-sulf...)
Affinity DataIC50:  70nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed