BDBM28464 (2R)-3-methyl-2-({11-[(propoxycarbonyl)amino]-8-oxatricyclo[7.4.0.0^{2,7}]trideca-1(13),2(7),3,5,9,11-hexaene-4-}sulfonamido)butanoic acid::dibenzofuran (DBF) scaffold, (R)-10

SMILES CCCOC(=O)Nc1ccc2c(c1)oc1ccc(cc21)S(=O)(=O)N[C@H](C(C)C)C(O)=O

InChI Key InChIKey=KKGJFHSYGOMRAH-LJQANCHMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28464   

TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28464((2R)-3-methyl-2-({11-[(propoxycarbonyl)amino]-8-ox...)
Affinity DataIC50:  109nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28464((2R)-3-methyl-2-({11-[(propoxycarbonyl)amino]-8-ox...)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed