BDBM284848 4-(6-(4-amino-5-(1-cyclopropyl-1H-pyrazol-5-yl)pyrrolo[2,1-f] [1,2,4]triazin-7-yl)-4-fluoro-1H-indazol-1-yl)tetrahydro-2H- thiopyran 1,1-dioxide::US10023576, Example 38

SMILES Nc1ncnn2c(cc(-c3ccnn3C3CC3)c12)-c1cc(F)c2cnn(C3CCS(=O)(=O)CC3)c2c1

InChI Key InChIKey=MDGBXPWTSRFZTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284848   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM284848(4-(6-(4-amino-5-(1-cyclopropyl-1H-pyrazol-5-yl)pyr...)
Affinity DataIC50:  12nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent