BDBM285156 4-[3-(cyclopropylmethoxy)-6- methylsulfonylpyridin-2-yl]-7-fluoro-2- methylisoquinolin-1-one::BDBM486000::US10023592, Example 201
SMILES Cn1cc(-c2nc(ccc2OCC2CC2)S(C)(=O)=O)c2ccc(F)cc2c1=O
InChI Key InChIKey=JORWJXZWMRRVDZ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 285156
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair