BDBM285521 5-({2-[4-(5-Chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-4-methoxybutanoyl}amino)-N-(2-methoxyethyl)pyrazolo[1,5-a]pyridine-3-carboxamide (racemate)::US10077265, Example 8

SMILES COCCNC(=O)c1cnn2ccc(NC(=O)C(CCOC)n3cc(OC)c(cc3=O)-c3cc(Cl)ccc3C#N)cc12

InChI Key InChIKey=FAUPYRQOQINXOL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285521   

TargetPlasma kallikrein(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM285521(5-({2-[4-(5-Chloro-2-cyanophenyl)-5-methoxy-2-oxop...)
Affinity DataIC50:  3.80nMpH: 7.4 T: 2°CAssay Description:To determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the reac...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM285521(5-({2-[4-(5-Chloro-2-cyanophenyl)-5-methoxy-2-oxop...)
Affinity DataIC50:  29nMpH: 7.4 T: 2°CAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent