BDBM285523 5-({2-[4-(5-Chloro-2-cyanophenyl)-5-methoxy-2-oxopyridin-1(2H)-yl]-4-methoxybutanoyl}amino)-N-[2-(trifluoromethoxy)ethyl]pyrazolo[1,5-a]pyridine-3-carboxamide (racemate)::US10077265, Example 10
SMILES COCCC(C(=O)Nc1ccn2ncc(C(=O)NCCOC(F)(F)F)c2c1)n1cc(OC)c(cc1=O)-c1cc(Cl)ccc1C#N
InChI Key InChIKey=DDOFNAVOJKWETH-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 285523
Affinity DataIC50: 9.5nMpH: 7.4 T: 2°CAssay Description:To determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the reac...More data for this Ligand-Target Pair
Affinity DataIC50: 47nMpH: 7.4 T: 2°CAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair