BDBM285605 1-(2-(4-(5-chloro-2-fluorobenzoyl)piperidin-1-yl)-3-(isopropylamino)-7,8-dihydropyrido[3,4-b]pyrazin-6(5H)-yl)ethanone::US10077266, Example 87

SMILES CC(C)Nc1nc2CN(CCc2nc1N1CCC(CC1)Oc1cc(Cl)ccc1F)C(C)=O

InChI Key InChIKey=BXCHXINRXDZGFI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285605   

TargetG-protein coupled receptor 6(Homo sapiens (Human))
Takeda Pharmaceutical

US Patent
LigandPNGBDBM285605(1-(2-(4-(5-chloro-2-fluorobenzoyl)piperidin-1-yl)-...)
Affinity DataIC50:  1.38E+4nMAssay Description:This cell based assay measures the ability of compounds to inhibit the constitutive cAMP activity of GPR6 receptor expressed in CHO-K1 cells. CHO cel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent