BDBM285652 5-ethyl-6-[4-(furo[2,3-d]pyrimidin-4-yloxy)phenyl]-1-methylpyrimidine-2,4(1H,3H)-dione::US10077272, Example 18::US9868744, 18

SMILES CCc1c(-c2ccc(Oc3ncnc4occc34)cc2)n(C)c(=O)[nH]c1=O

InChI Key InChIKey=WLXKTNRUSCBRJF-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285652   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM285652(5-ethyl-6-[4-(furo[2,3-d]pyrimidin-4-yloxy)phenyl]...)
Affinity DataKi:  274nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM285652(5-ethyl-6-[4-(furo[2,3-d]pyrimidin-4-yloxy)phenyl]...)
Affinity DataKi:  274nMpH: 7.4Assay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent