BDBM285826 (6R,7R,8R)-6,7-dihydroxy-4-azaspiro[2.5]octane-8-carbonitrile::US10081601, Example 8::US9796680, Example 8

SMILES O[C@@H]1CNC2(CC2)[C@H](C#N)[C@H]1O

InChI Key InChIKey=WOKVFVFSTFFEDJ-FSDSQADBSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285826   

TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Alectos Therapeutics

US Patent
LigandPNGBDBM285826((6R,7R,8R)-6,7-dihydroxy-4-azaspiro[2.5]octane-8-c...)
Affinity DataIC50:  75nMAssay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
Alectos Therapeutics

US Patent
LigandPNGBDBM285826((6R,7R,8R)-6,7-dihydroxy-4-azaspiro[2.5]octane-8-c...)
Affinity DataIC50:  75nMpH: 7.0Assay Description:Various concentrations of test compounds were prepared in DMSO and then diluted into buffer consisting of 50 mM sodium phosphate 0.25% w/v sodium tau...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent