BDBM285912 3-((S)-1-{4-[6-Amino-5-(1H-pyrazol-4-yl)-pyrimidin-4-yl]-piperazin-1-yl}-2-azetidin-1-yl-ethyl)-benzonitrile::US10080750, Compound 97::US9662330, Compound 97

SMILES Nc1ncnc(N2CCN(CC2)[C@H](CN2CCC2)c2cccc(c2)C#N)c1-c1cn[nH]c1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285912   

TargetRibosomal protein S6 kinase beta-1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM285912(3-((S)-1-{4-[6-Amino-5-(1H-pyrazol-4-yl)-pyrimidin...)
Affinity DataIC50:  3.70E+3nMAssay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRibosomal protein S6 kinase beta-1 [T412E](Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM285912(3-((S)-1-{4-[6-Amino-5-(1H-pyrazol-4-yl)-pyrimidin...)
Affinity DataIC50:  3.70E+3nMpH: 7.5Assay Description:P70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components was then added to the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent