BDBM286012 (E)-Methyl N-[8-({2-[5-chloro-2-(1H-1,2,3,4-tetrazol-1-yl)phenyl]ethyl}carbamoyl)-2,10-dioxo-1,2,3,4,7,8,9,10-octahydro-1,9-benzodiazacyclododecin-13-yl]carbamate::US10081623, Example 25

SMILES Clc1ccc(c(CCNC(=O)[C@H]2CC=CCCC(=O)Nc3ccccc3C(=O)N2)c1)-n1cnnn1

InChI Key InChIKey=UDJKQCZYNZIIJX-HXUWFJFHSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 286012   

TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM286012((E)-Methyl N-[8-({2-[5-chloro-2-(1H-1,2,3,4-tetraz...)
Affinity DataKi: <5nMpH: 7.4Assay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent