BDBM286057 N-(2-(4-Chlorophenyl)-1-ethyl-1H-indol-5-yl)-2-(difluoromethyl)-5-(((1-methylcyclopropanecarbonyl)amino)methyl)nicotinamide::US10081629, Example 42

SMILES CCn1c(cc2cc(NC(=O)c3cc(CNC(=O)C4(C)CC4)cnc3C(F)F)ccc12)-c1ccc(Cl)cc1

InChI Key InChIKey=SKKHLABJUDRQDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 286057   

TargetProstaglandin E synthase(Homo sapiens (Human))
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM286057(N-(2-(4-Chlorophenyl)-1-ethyl-1H-indol-5-yl)-2-(di...)
Affinity DataIC50:  7.21nMAssay Description:mPGES1 was diluted with assay buffer and added into plate at 49 μL/well supplemented with 1 μL of compound (the final concentration of each...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent