BDBM286250 N-(1H-Benzoimidazol-2-yl)-3-(6-oxo-3-pyrimidin-5-yl-6H-pyridazin-1-ylmethyl)-benzamide::US9567320, Example 8
SMILES O=C(Nc1nc2ccccc2[nH]1)c1cccc(Cn2nc(ccc2=O)-c2cncnc2)c1
InChI Key InChIKey=XRKNHCDVUQOHPG-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 286250
Affinity DataIC50: 550nMAssay Description:IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Serine/Threonine generic peptidic substrate (STK: 61ST1BLC from CisBio International ba...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:IRAK1 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712)) In this assay, IRAK-1 hydrolyses ATP and autophosphorylates.Measurement of IRA...More data for this Ligand-Target Pair