BDBM286557 US9566312, Compound 2.6.3

SMILES CC[C@H](NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)[C@H](C)COCC(=O)N1CCN(C)CC1)C(C)C)C(=O)N(C)[C@H](C)C(C)=O

InChI Key InChIKey=NZMJWNAGUNOQAX-ZGJFSDCUSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 286557   

TargetPeptidyl-prolyl cis-trans isomerase A(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM286557(US9566312, Compound 2.6.3)
Affinity DataKd:  1.5nMpH: 7.4Assay Description:Binding of inhibitors to expressed cyclophilins was determined using surface plasmon resonance (SPR) experiments. Briefly, avi-tagged cyclophilin pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase F, mitochondrial(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM286557(US9566312, Compound 2.6.3)
Affinity DataKd:  0.5nMpH: 7.4Assay Description:Binding of inhibitors to expressed cyclophilins was determined using surface plasmon resonance (SPR) experiments. Briefly, avi-tagged cyclophilin pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPeptidyl-prolyl cis-trans isomerase B(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM286557(US9566312, Compound 2.6.3)
Affinity DataKd:  0.800nMpH: 7.4Assay Description:Binding of inhibitors to expressed cyclophilins was determined using surface plasmon resonance (SPR) experiments. Briefly, avi-tagged cyclophilin pro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent