BDBM286630 7-((S)-2-Aminomethyl-pyrrolidin-1-ylmethyl)-8-chloro-3-(5-chloro-2-ethanesulfonyl-benzyl)-6-trifluoromethyl-1H-quinazoline-2,4-dione::US9567304, Compound F-79

SMILES CCS(=O)(=O)c1ccc(Cl)cc1Cn1c(=O)[nH]c2c(Cl)c(CN3CCC[C@H]3CN)c(cc2c1=O)C(F)(F)F

InChI Key InChIKey=WMNQSYGEIAMVJD-HNNXBMFYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 286630   

TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandPNGBDBM286630(7-((S)-2-Aminomethyl-pyrrolidin-1-ylmethyl)-8-chlo...)
Affinity DataIC50:  17nMT: 2°CAssay Description:DDR1 binding activity was measured using the LanthaScreen(Registered trademark) Eu Kinase Binding Assay (manufactured by Life Technologies Corporatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent