BDBM287215 US9567339, Example A.4.11

SMILES Cc1c(NC2COC2)cccc1-c1ccc(C(N)=O)c2[nH]c(cc12)C1=CCN(CC1)S(C)(=O)=O

InChI Key InChIKey=HMKNLOZSQLMAPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287215   

TargetTyrosine-protein kinase BTK [393-659](Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM287215(US9567339, Example A.4.11)
Affinity DataIC50: <100nMpH: 6.5 T: 2°CAssay Description:The in-house BTK corresponds to recombinant human catalytic domain (aa 393-659), which was expressed in SF9 cells with an N-terminal his tag and puri...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent