BDBM287593 US10420768, Compound C-47::US9567341, Compound C-47

SMILES CN(C1CCN(CC(F)(F)c2ccc(C)cn2)CC1)c1ncnc2[nH]ccc12

InChI Key InChIKey=KXZSHSUBGGJHMF-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 287593   

TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM287593(US10420768, Compound C-47 | US9567341, Compound C-...)
Affinity DataIC50:  140nMpH: 7.35Assay Description:The assay was performed on hERG channel stably expressed in HEK293 cells. The cells were cultured at 37° C. in a humidified CO2 incubator in the grow...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM287593(US10420768, Compound C-47 | US9567341, Compound C-...)
Affinity DataIC50: >1.00E+7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2B(Homo sapiens (Human))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM287593(US10420768, Compound C-47 | US9567341, Compound C-...)
Affinity DataIC50:  140nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2A(Homo sapiens (Human))
Rugen Holdings (Cayman)

US Patent
LigandPNGBDBM287593(US10420768, Compound C-47 | US9567341, Compound C-...)
Affinity DataIC50: >1.00E+7nMpH: 7.4Assay Description:Inhibitory activities of test compounds on 5 major isoforms of CYP P450 were evaluated by using pooled human liver microsome (HLM, purchased from BD ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent