BDBM287872 6-({4-[(3-Methylazetidin-1-yl)carbonyl]bicyclo[2.2.2]oct-1-yl}carbonyl)-6,11-dihydro-5H-pyrido[2,3-b][1,5]benzodiazepine::US10086000, Example 89::US10508108, Example 89
SMILES CC1CN(C1)C(=O)C12CCC(CC1)(CC2)C(=O)N1Cc2cccnc2Nc2ccccc12
InChI Key InChIKey=BTLDQLASAZXKGG-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 287872
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 4.20E+3nMAssay Description:Each test compound (10 mM stock in DMSO) is diluted in DMSO to make a 10-point, 3-fold dilution series. 125 nL of each dilution or DMSO alone is disp...More data for this Ligand-Target Pair
TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataIC50: 4.20E+3nMpH: 7.0 T: 2°CAssay Description:Each test compound (10 mM stock in DMSO) is diluted in DMSO to make a 10-point, 3-fold dilution series. 125 nL of each dilution or DMSO alone is disp...More data for this Ligand-Target Pair