BDBM287972 N-(4-(4-((2,2- diphenylpropyl)amino)quinazolin-2- yl)phenyl)methanesulfonamide::US10087148, Example 39

SMILES CC(CNc1nc(nc2ccccc12)-c1ccc(NS(C)(=O)=O)cc1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=ZAXWEIRTLIHPRQ-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 287972   

TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
The United States Of America As Represented By The Secretary, Department Of Health And Human Services Office Of Technology Transfer, National Institute Of Health

US Patent
LigandPNGBDBM287972(N-(4-(4-((2,2- diphenylpropyl)amino)quinazolin-2- ...)
Affinity DataEC50:  16nMpH: 7.4Assay Description:Uptake inhibition assay for the dopamine transporter was conducted in rat brain synaptosomes as described elsewhere with minor modifications (Rothman...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent