BDBM28820 N-[4-(difluoromethoxy)phenyl]-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine::triazolopyrimidine-based compound, DSM88

SMILES Cc1cc(Nc2ccc(OC(F)F)cc2)n2ncnc2n1

InChI Key InChIKey=VPBMXCQRVKYXSF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28820   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University Of Washington At Seattle

LigandPNGBDBM28820(N-[4-(difluoromethoxy)phenyl]-5-methyl-[1,2,4]tria...)
Affinity DataIC50:  2.50E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Washington At Seattle

LigandPNGBDBM28820(N-[4-(difluoromethoxy)phenyl]-5-methyl-[1,2,4]tria...)
Affinity DataIC50:  2.80E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed