BDBM28821 5-methyl-N-(4-nitrophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine::triazolopyrimidine-based compound, DSM99

SMILES Cc1cc(Nc2ccc(cc2)[N+]([O-])=O)n2ncnc2n1

InChI Key InChIKey=VEPQYHXUPOYESS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28821   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University Of Washington At Seattle

LigandPNGBDBM28821(5-methyl-N-(4-nitrophenyl)-[1,2,4]triazolo[1,5-a]p...)
Affinity DataIC50:  3.70E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Washington At Seattle

LigandPNGBDBM28821(5-methyl-N-(4-nitrophenyl)-[1,2,4]triazolo[1,5-a]p...)
Affinity DataIC50:  4.30E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed