BDBM28830 5-methyl-N-(2,3,5,6-tetrafluorophenyl)-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine::triazolopyrimidine-based compound, DSM132

SMILES Cc1cc(Nc2c(F)c(F)cc(F)c2F)n2ncnc2n1

InChI Key InChIKey=KAGCULZRDUQOKH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28830   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University Of Washington At Seattle

LigandPNGBDBM28830(5-methyl-N-(2,3,5,6-tetrafluorophenyl)-[1,2,4]tria...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Washington At Seattle

LigandPNGBDBM28830(5-methyl-N-(2,3,5,6-tetrafluorophenyl)-[1,2,4]tria...)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed