BDBM28839 5-methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine::triazolopyrimidine-based compound, DSM122

SMILES Cc1cc(Nc2ccc(C)c(c2)C(F)(F)F)n2ncnc2n1

InChI Key InChIKey=ZEPMPJCWXKPMQM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 28839   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University Of Washington At Seattle

LigandPNGBDBM28839(5-methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]-[1...)
Affinity DataIC50:  1.55E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Homo sapiens (Human))
University Of Washington At Seattle

LigandPNGBDBM28839(5-methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]-[1...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
University Of Washington At Seattle

LigandPNGBDBM28839(5-methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]-[1...)
Affinity DataIC50:  7.30E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed