BDBM288629 (E)-3-(3,5-difluoro-4-((1S,3R/1R,3S)-2-(2-fluoro-2-methylpropyl)-3-methyl-6-(4-methyl-3-oxopiperazin-1-yl)-1,2,3,4-tetrahydroisoquinolin-1-yl)phenyl)acrylic acid::US10087191, Example 39
SMILES CC1Cc2cc(ccc2C(N1CC(C)(C)F)c1c(F)cc(\C=C\C(O)=O)cc1F)N1CCN(C)C(=O)C1
InChI Key InChIKey=NWSPDFJGJVGZES-VMPITWQZSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 288629
Affinity DataIC50: 14.2nMAssay Description:The compounds of the present invention have an inhibition effect on the binding of E (estrogen) to ER (estrogen receptor), thereby blocking the bindi...More data for this Ligand-Target Pair