BDBM288965 US10092563, Compound 102
SMILES Nc1ncnc(N[C@@H](C2CC2)c2nc3cccc(Cl)c3c(=O)n2N2CCNCC2)c1C#N
InChI Key InChIKey=MLKPMESVKZNTJI-KRWDZBQOSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 288965
TargetPhosphatidylinositol 3-kinase regulatory subunit beta(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 5.70E+4nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: >1.00E+7nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 2.00E+3nMpH: 7.4Assay Description:TR-FRET monitored the formation of 3,4,5-inositol triphosphate molecule that competed with fluorescently labeled PIPS for binding to the GRP-1 plecks...More data for this Ligand-Target Pair