BDBM289042 US10093650, Example 19::US10329273, Example 19::US11479538, Example 19

SMILES CC(O)c1ccc(s1)C1=C(C(=O)N[C@@](C1)(c1ccc(OCCCC(F)(F)F)cc1)C(F)(F)F)n1nn[nH]c1=O

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 289042   

TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM289042(US10093650, Example 19 | US10329273, Example 19 | ...)
Affinity DataIC50:  10nMpH: 7.4Assay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM289042(US10093650, Example 19 | US10329273, Example 19 | ...)
Affinity DataIC50:  10nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAlpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM289042(US10093650, Example 19 | US10329273, Example 19 | ...)
Affinity DataIC50:  10nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent