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BDBM289093 6-hydroxy-2,4-dioxo-N-(4-(trifluoromethylsulfonamido)phenyl)-1,2,3,4-tetrahydropyrimidine-5-carboxamide::US10093658, Compound Formula (Ic)

SMILES: Oc1[nH]c(=O)[nH]c(=O)c1C(=O)Nc1ccc(NS(=O)(=O)C(F)(F)F)cc1

InChI Key: InChIKey=QLLAJLXIWXBPAY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289093   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Xanthine dehydrogenase/oxidase


(Homo sapiens (Human))
BDBM289093
PNG
(6-hydroxy-2,4-dioxo-N-(4-(trifluoromethylsulfonami...)
Show SMILES Oc1[nH]c(=O)[nH]c(=O)c1C(=O)Nc1ccc(NS(=O)(=O)C(F)(F)F)cc1
Show InChI InChI=1S/C12H9F3N4O6S/c13-12(14,15)26(24,25)19-6-3-1-5(2-4-6)16-8(20)7-9(21)17-11(23)18-10(7)22/h1-4,19H,(H,16,20)(H3,17,18,21,22,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.01E+5n/an/an/an/an/an/a



Acquist LLC

US Patent


Assay Description
Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...


US Patent US10093658 (2018)

More data for this
Ligand-Target Pair