BDBM289112 N-(4-(2H-tetrazol-5-yl)phenyl)-6-hydroxy-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide::US10093658, Compound Formula (IIa)

SMILES Oc1[nH]c(=O)[nH]c(=O)c1C(=O)Nc1ccc(cc1)-c1nnn[nH]1

InChI Key InChIKey=NMLBBWYWOIBCIY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 289112   

TargetXanthine dehydrogenase/oxidase(Homo sapiens (Human))
Acquist

US Patent
LigandPNGBDBM289112(N-(4-(2H-tetrazol-5-yl)phenyl)-6-hydroxy-2,4-dioxo...)
Affinity DataIC50:  680nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Acquist

US Patent
LigandPNGBDBM289112(N-(4-(2H-tetrazol-5-yl)phenyl)-6-hydroxy-2,4-dioxo...)
Affinity DataIC50:  9.54E+3nMAssay Description:URAT1 (SLC22A12) activity was evaluated in a cellular uptake assay using a 96-well plate with stably transfected URAT-1/CHO cells. 3H-orotate was use...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent