BDBM289428 (S)-1-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl)-1-(3-morpholinobicyclo[1.1.1]pentan-1-yl)-1H-imidazol-2-yl)-2,2,2-trifluoroethanol::US10093664, Example 8a::US11560366, Example 16

SMILES Nc1ncc(cc1OC(F)(F)F)-c1cn(c(n1)[C@@H](O)C(F)(F)F)C12CC(C1)(C2)N1CCOCC1

InChI Key InChIKey=UPDAFITWGUHASN-RWBZWWBESA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 289428   

TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM289428((S)-1-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl...)
Affinity DataKd:  0.360nMAssay Description:A fusion protein of full length of human DLK (amino acids 1-859) and the DNA binding domain of NFkB was expressed in transiently transfected HEK293 c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Board Of Regents, The University Of Texas System

US Patent
LigandPNGBDBM289428((S)-1-(4-(6-amino-5-(trifluoromethoxy)pyridin-3-yl...)
Affinity DataKd:  0.360nMAssay Description:The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent