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BDBM289439 4-(3-(2-cyclopropyl-4-(1H-pyrrolo[3,2-b]pyridin-6-yl)-1H-imidazol-1-yl)bicyclo[1.1.1]pentan-1-yl)morpholine::US10093664, Example 20

SMILES: C1CC1c1nc(cn1C12CC(C1)(C2)N1CCOCC1)-c1cnc2cc[nH]c2c1

InChI Key: InChIKey=AIMMCWSDFDBUMU-UHFFFAOYSA-N

Data: 1 Kd

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 289439   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase 12


(Homo sapiens)
BDBM289439
PNG
(4-(3-(2-cyclopropyl-4-(1H-pyrrolo[3,2-b]pyridin-6-...)
Show SMILES C1CC1c1nc(cn1C12CC(C1)(C2)N1CCOCC1)-c1cnc2cc[nH]c2c1
Show InChI InChI=1S/C22H25N5O/c1-2-15(1)20-25-19(16-9-18-17(24-10-16)3-4-23-18)11-27(20)22-12-21(13-22,14-22)26-5-7-28-8-6-26/h3-4,9-11,15,23H,1-2,5-8,12-14H2
PDB

KEGG

UniProtKB/SwissProt

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AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/a 7.50E+3n/an/an/an/an/a



Board of Regents, The University of Texas System

US Patent


Assay Description
The DLK dissociation constants (Kd) have been determined in the KINOMEscan KdELECT Service at DiscoveRx. A fusion protein of full length of human DLK...


US Patent US10093664 (2018)

More data for this
Ligand-Target Pair